Improving Lives

Living with type 1 diabetes (T1D) can bring struggles, stress, and countless challenges – for the person with the disease and their loved ones. That is why JDRF is working to advance T1D research and technology that will make every day safer and healthier until a cure is found. Read below to see the areas of research JDRF supports to improve lives.

Developing Better, Smaller, Less Intrusive Devices

Imagine wearing a T1D device that required next to no attention from the wearer? Our research into devices is aiming for that goal by developing artificial pancreas systems that provide fully automated insulin delivery from a single miniaturized or even implantable device. We are also supporting development of devices that continuously monitor ketones alongside glucose to minimize the risk of diabetic ketoacidosis (DKA).

Currently available technologies that were developed in part with JDRF support are improving and even saving lives, every day. By monitoring glucose levels, providing information to enable accurate insulin dosing, sending high and low alerts even in the middle of the night – these innovations are helping people living with T1D and their caregivers to do what they want and be who they want.

Advancing Next-Generation Insulins and Other Drugs that Improve Glucose Control

Insulin therapy has come a long way since its discovery over 100 years ago, but it is still far from perfect. JDRF research in this area supports the development of glucose-responsive or “smart” insulins, which would be activated in the bloodstream only when glucose levels increased, removing carb-counting and dosing challenges, and eliminating the risk of hypoglycemia.

We also support the development of adjunctive therapies – new medicines that can be taken alongside insulin – that will improve glucose control and other metabolic imbalances in people with T1D, as well as potentially reduce the risk of complications.

Reducing the Risk and Treatment of Complications

JDRF is also supporting work to better predict, prevent and treat complications of T1D in people who have lived with the disease for decades. Our areas of focus are diabetic retinopathy (which can lead to blindness), diabetic kidney disease, and cardiovascular disease.

Improving Mental Health in T1D

Mental health remains an under-researched, yet essential aspect of T1D management. People with T1D are at increased risk of mental health issues including anxiety, depression, eating disorders and diabetes distress.

JDRF’s research in this area supports development and testing of behavioral health interventions that will improve the mental health of people T1D, and may also improve clinical outcomes such as glucose control and risk of complications. We also aim to capture psychosocial outcomes in any clinical research that we fund. In parallel with our research in this area, we offer community support and connection.

Learn more about JDRF-funded research in Canada on Improving Lives. JDRF-CIHR Funded Projects
370+
supported projects worldwide
70%
of research funding invested in cure research
$3B+
invested in T1D research funding globally
19
countries with active grants
60+
Supported T1D clinical trials

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