Investigator Biography

Bruce Perkins, MD, MPH

Dr. Bruce Perkins is Assistant Professor and Endocrinologist at the University of Toronto’s University Health Network practicing general endocrinology, and a Diabetes Complications Clinician-Investigator.

Dr. Perkins is a Canadian Diabetes Association (CDA) Scholar and receives JDRF, Canadian Institutes of Health Research (CIHR), and Banting and Best Diabetes Center funding. His research methods focus on cohort studies and clinical trials in diabetic nephropathy and neuropathy.

Dr. Perkins’ particular interests are in the identification of valid early phenotypes of these complications, and the natural history and determinants of the early phenotypes. He has also described novel phenotypes for early nephropathy and he has introduced “Early GFR Loss” as the alternative to microalbuminuria as a predictive marker, using the serial analysis of serum cystatin C. For early neuropathy, he has developed the operating characteristics of Corneal Confocal Microscopy as a method to analyze early small fiber morphological abnormalities as an alternative to intra-epidermal nerve fiber analysis by skin biopsy.

Dr. Perkins also has a major focus on technologies in diabetes care including the use of insulin pumps and continuous glucose monitoring in clinical trials and clinical practice. He chaired the Ministry of Health’s expert panel for Insulin Pump Coverage for adults in Ontario.

He obtained his MD and Internal Medicine Residency training at the University of Toronto, endocrinology subspecialty training at Harvard University and the Joslin Diabetes Center, and his Masters of Public Health in Epidemiology at the Harvard School of Public Health.

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