JDRF's Research Frontline e-mail newsletter is published approximately every 6 to 8 weeks to provide the latest information about research on Type 1 diabetes and its complications.

Subscribe by sending an e-mail to communications@jdrf.ca. Please include "Subscribe Research Frontline" in the subject line.

Read the current issues:

Issue 11-09

  • Targeting the B cell prevents diabetes in mice
  • Successful encapsulation of beta cell precursors
  • Why beta cell regeneration slows with age
  • With the switch of a gene, non-insulin producing cells make insulin

Issue 08-09

  • Connecting people with diabetes to clinical trials
  • Two drugs for hypertension may address diabetic retinopathy
  • In development: A novel oral vaccine for type 1 diabetes autoimmunity
  • JDRFI, GNF form innovative partnership
  • Researchers gather to discuss the complications of diabetes and obesity

Issue 07-09

  • JDRFI Partner Bayhill Enters Collaboration with Genentech to Develop Type 1 Vaccine

Issue 06-09

  • Progress on the stem cell front
  • A gene in mice may hold clues to treatments for people
  • In the near future, a clinical trial of regulatory T cells

Issue 05-09

  • Progress in the field of islet transplantation
  • Cancer drugs reverse type 1 diabetes in mice
  • A potential new approach for treating diabetic eye disease

Issue 03-09

  • Stem cell policy repealed
  • A promising new therapy
  • Metabolic abnormalities precede autoimmunity in type 1 children
  • Scientists find a way to encourage the replication of adult human beta cells

Issue 02-09

  • An important new field of study: the epigenetics of type 1 diabetes
  • A new gastrin combination therapy reverses diabetes in mice
  • Type 1 diabetes and celiac disease are genetically linked

Issue 12-08

  • A link between diabetes prevention and the hygiene hypothesis
  • The protein interferon-alpha appears to trigger type 1 diabetes
  • Transplanted islets survive in mice without the use of immunosuppressive drugs

Issue 10-08

  • Towards evaluating pancreatic beta cells in vivo
  • Using dendritic cells to control autoimmunity
  • Scientific presentations focus on adults with Type 1 diabetes

Issue 05-08

  • Success in growing human beta cells in vitro
  • An antibody therapy activates key regulatory cells, alters disease progression
  • Human stem cells, when translplanted into mice, are fully functional

Issue 03-08

  • An “Inflammatory Signature” In Both New-Onset and At-Risk Patients
  • Genetics Protects Some Individuals From Diabetic Kidney Disease
  • At Last, The Elusive Pancreatic Progenitor Cell


Read previous issues:

Issue 07-07

  • Tumor-Suppressing Protein Regulates Beta Cell Growth
  • Human Skin Cells Reprogrammed to Embryonic State

Issue 06-07

  • JDRF Industry Partners in Drug Development Alliances with Major Pharma Companies
  • Fatty Acid in Diet May Lower Type 1 Diabetes Risk
  • Current Transplant Drugs May Hinder Beta Cell Regeneration
  • Discovery of Fourth Diabetes Antibody Should Aid Prediction

Issue 05-07

  • Taking Antibody Orally May Help Block Diabetes
  • Stopping Islet Inflammation May Be Key for Type 1 Prevention
  • Gene Provides Clues To Development of Type 1

Issue 04-07

  • "Diabulimia": young girls with Type 1 diabetes skipping insulin doses to lose weight
  • Mouse Skin Cells Reprogrammed to Embryonic State
  • Powerful Research Method Finds Four New Type 1 Diabetes Genetic Regions

Issue 03-07

  • Clinical Trial of Diabetes Regenerative Therapy Shows Positive Results
  • Glucagon May Add Another Dimension To Artificial Pancreas
  • Immune System Pathway May Be Key Route for Preventing Diabetes
  • Scientific Paper Retracted

Issue 02-07

  • Natural Compounds Prevent Diabetes By Blocking Immune Cell Channel
  • Amniotic Fluid-Derived Stem Cells Show Potential
  • Drug Shown to Protect Against Diabetic Retinopathy

Issue 1-07

  • Agreement to Develop Complications Drugs Results From 16 Years of Research
  • Bone Marrow Cells From Humans Repair Islet Cells in Mice
  • Novocell Creates Insulin-Secreting Cells From Embryonic Stem Cells
  • Researchers Clarify Initial Stage of Autoimmune Attack